These public health challenges are likely to surge along with growth in the proportion of adults over age 65 in the United States and around the world ( CDC, 2013 NIA, 2007). This is important because age-related neurodegenerative conditions like AD are associated with enormous costs from morbidity, mortality, and loss of independence ( Barnes and Yaffe, 2011 Hurd et al., 2013). Research has demonstrated the protective and restorative potential of physical activity and fitness for age-related cognitive decline and neurodegenerative diseases including Alzheimer’s Disease (AD) ( Buchman et al., 2012 Colcombe and Kramer, 2003 Hamer and Chida, 2009 Liu et al., 2012 Smith et al., 2010 Sofi et al., 2011). ![]() Overall, our findings provide further support that cardiorespiratory fitness is an important factor in moderating the adverse effects of aging on cognitively and clinically relevant functional brain networks. Furthermore, our results suggest that the positive association of fitness with brain function can occur independent of habitual physical activity. Consistent with this prediction, and extending on previous research, we showed that cardiorespiratory fitness has a positive relationship with functional connectivity of several cortical networks associated with age-related decline, and effects were strongest in the Default Mode Network (DMN). Based on these results and previous research, we predicted that individual differences in fitness and physical activity would be most strongly associated with functional integrity of the networks most sensitive to aging. To build context for fitness and physical activity associations in older adults, we first demonstrate that young adults have greater within-network functional connectivity across a broad range of cortical association networks. The primary goal of the current study was to empirically evaluate the independent relationships between physical activity and fitness with functional brain health among healthy older adults, as measured by the functional connectivity of cognitively and clinically relevant resting state networks. However, significant gaps remain in the understanding of how physical activity and fitness protect the brain from adverse effects of brain aging. ![]() Full details of the vehicles, the opening times, and COVID19 guidelines are available on their website.Greater physical activity and cardiorespiratory fitness are associated with reduced age-related cognitive decline and lower risk for dementia. A visit is highly recommended.īond In Motion at the Petersen Automotive Museum in Los Angeles is open until 30 October 2022īond In Motion opens September 25th, with tickets costing $16 for adults, $14 for seniors, and $11 for children - paid parking is also available onsite. Rarely will you find such a comprehensive collection of vehicles of all types located in one place. If you are at all interested in the history of automotives, then The Petersen is well worth a visit for this aspect alone. These vehicles will be shown at Beaulieu motor museum - the original home of Bond In Motion - opening to coincide with the release of the film. The biggest disappointed perhaps is the fact that there are currently no vehicles from No Time To Die on display here. Hiller UH-12C helicopter, From Russia With Loveįor fans of Aston Martin, there is one of only ten DB10s from SPECTRE, the bullet-mangled Aston Martin DBS from Quantum of Solace, the somewhat flattened world-record-breaking Aston Martin DBS from “Casino Royale”, a very visible Vanquish from Die Another Day, the winterised V8 Vantage from The Living Daylights, as well as the famous DB5. However, there are other gems that may not have been seen before, such as the full-size working Neptune submersible from For Your Eyes Only and Sanchez’s Cessna Skyhawk from Licence To Kill, along with boats, buggies, and bikes from the rest of the series. Lotus Esprit 'Wet Nellie', The Spy Who Loved Me While the exhibition isn’t exactly the same collection that was on display in London, there are many familiar vehicles on display here including the Aston Martin DB5 and the “Wet Nellie” Lotus Esprit S1. ![]() The fine collection of iconic vehicles from the finest film series can now be admired in The Petersen Automotive Museum in Los Angeles - arguably one of the finest automotive museums in the world. After many years the Bond In Motion exhibition left the London Film Museum in January 2021 and settled down in the United States.
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